Systematic Identification of Barriers to Human iPSC Generation

The identification of genetic barriers to reprogramming is important for increasing reprogramming efficiency as well as understanding the mechanisms of pluripotency. We have performed a genome wide screen for barriers to reprogramming using RNA interference.

Visualize the screen

Browse and search the screen hits. Compare genes for screen enrichment ... View details »

Screen hit kinetics

Browse expression, protein concentration, and chromatin dynamics during reprogramming for screen hit orthologs in mouse ... View details »

Pathway analysis

Browse functional annotation clusterings for screen hits ...

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